(2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid

This compound is a synthetic small molecule and an amino acid analog structurally related to glutamine. It acts as an inhibitor of leukotriene A4 hydrolase, the enzyme responsible for converting leukotriene A4 to leukotriene B4 in the arachidonic acid metabolism pathway. Leukotriene B4 is a potent pro-inflammatory mediator involved in various inflammatory diseases. The compound has been studied primarily as a research tool and investigative agent rather than for clinical use, with no approved indications or advanced clinical trials reported[1][6]. Its primary mechanism of action is inhibition of leukotriene A4 hydrolase, potentially modulating inflammatory responses.

Other names

N-[4-(phenylmethoxy)phenyl]-L-glutamineN5-[4-(Phenylmethoxy)phenyl]-L-glutamine(2S)-2-amino-4-{[4-(benzyloxy)phenyl]carbamoyl}butanoic acidAmino acid analog, 4f